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- assertion description "[To assess the possible association between the PTPN22 gene 1858C-->T polymorphism and the susceptibility to Henoch-Sch?nlein purpura (HSP) and determine if this polymorphism is implicated in the severity of this systemic vasculitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.