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Matches in Nanopublications for { ?s ?p "10-Hz train stimulation also caused changes in expression of a MEF2-driven luciferase reporter introduced into the fibers via an adenoviral construct (Wilkins et al., 2004). 5 h of repetitive stimulation (5-s duration 10-Hz trains every 50 s) followed by 19 h without stimulation caused luciferase activity in fiber culture extracts to approximately double compared with extracts from parallel unstimulated fiber cultures (Fig. 3 B). The same stimulation (5 h, followed by 19 h without stimulation) in the presence of the CaMK inhibitor KN-62 gave the same luciferase activity as control. Thus, KN-62 completely blocked the stimulation-dependent increase in MEF2 reporter activity, just as KN-62 completely blocked the stimulation-dependent efflux of HDAC4 from the nucleus (Fig. 2)." ?g. }

• _6 value "10-Hz train stimulation also caused changes in expression of a MEF2-driven luciferase reporter introduced into the fibers via an adenoviral construct (Wilkins et al., 2004). 5 h of repetitive stimulation (5-s duration 10-Hz trains every 50 s) followed by 19 h without stimulation caused luciferase activity in fiber culture extracts to approximately double compared with extracts from parallel unstimulated fiber cultures (Fig. 3 B). The same stimulation (5 h, followed by 19 h without stimulation) in the presence of the CaMK inhibitor KN-62 gave the same luciferase activity as control. Thus, KN-62 completely blocked the stimulation-dependent increase in MEF2 reporter activity, just as KN-62 completely blocked the stimulation-dependent efflux of HDAC4 from the nucleus (Fig. 2)." provenance.
• _6 value "10-Hz train stimulation also caused changes in expression of a MEF2-driven luciferase reporter introduced into the fibers via an adenoviral construct (Wilkins et al., 2004). 5 h of repetitive stimulation (5-s duration 10-Hz trains every 50 s) followed by 19 h without stimulation caused luciferase activity in fiber culture extracts to approximately double compared with extracts from parallel unstimulated fiber cultures (Fig. 3 B). The same stimulation (5 h, followed by 19 h without stimulation) in the presence of the CaMK inhibitor KN-62 gave the same luciferase activity as control. Thus, KN-62 completely blocked the stimulation-dependent increase in MEF2 reporter activity, just as KN-62 completely blocked the stimulation-dependent efflux of HDAC4 from the nucleus (Fig. 2)." provenance.