Matches in Nanopublications for { ?s ?p "A COOH-terminal Ser phosphorylation site of smMLCK provided the earliest evidence that the Ca2 sensitivity of smMLCK could be regulated: phosphorylation of this site reduces the affinity of MLCK for Ca2/CaM (increases KCaM) by 10-fold. This inhibitory Ser (Ser-512 in smMLCK) can be phosphorylated by cAMP-dependent kinase (PKA; Ref. 72) and also by other kinases (3; reviewed in Refs. 116, 181), but only when Ca/CaM is not bound to MLCK." ?g. }
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- _6 value "A COOH-terminal Ser phosphorylation site of smMLCK provided the earliest evidence that the Ca2 sensitivity of smMLCK could be regulated: phosphorylation of this site reduces the affinity of MLCK for Ca2/CaM (increases KCaM) by 10-fold. This inhibitory Ser (Ser-512 in smMLCK) can be phosphorylated by cAMP-dependent kinase (PKA; Ref. 72) and also by other kinases (3; reviewed in Refs. 116, 181), but only when Ca/CaM is not bound to MLCK." provenance.