Matches in Nanopublications for { ?s ?p "Because IL-18 induced AP-1 DNA binding activity, we investigated whether AP-1 complexes interact in vivo with the MMP9 promoter. We therefore performed ChIP assays on arterial SMCs that were either untreated or treated with IL-18. This analysis demonstrated that IL-18 treatment increased Fra-1 binding to the AP-1 site in vivo (Fig. 7C)." ?g. }
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- _5 value "Because IL-18 induced AP-1 DNA binding activity, we investigated whether AP-1 complexes interact in vivo with the MMP9 promoter. We therefore performed ChIP assays on arterial SMCs that were either untreated or treated with IL-18. This analysis demonstrated that IL-18 treatment increased Fra-1 binding to the AP-1 site in vivo (Fig. 7C)." provenance.