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Matches in Nanopublications for { ?s ?p "Because PDE3B is only ~10% as sensitive to cGMP inhibition, incubation of adipocytes, a cell type expressing only PDE3B, with nitrate donors, does not increase adipocyte cAMP (Manganiello and Degerman, 1999). In addition to these short-term regulatory effects, levels of PDE3 expression are increased after incubation of cells with cAMP-elevating agents, although the magnitude of this effect is PDE3 variant- and cell type-specific (Manganiello and Degerman, 1999; Shakur et al., 2001)." ?g. }

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