Matches in Nanopublications for { ?s ?p "Cotransfection of Jurkat cells with vGPCR and an NF-AT luciferase reporter plasmid showed that vGPCR activated NF-AT in a dose-dependent fashion, as judged by NF-AT luciferase reporter gene expression. The activation was calcineurin dependent because it was suppressed by cyclosporine A (CSA), a highly specific calcineurin inhibitor. Cotransfected expression constructs for NF-AT1 and NF-AT2 with vGPCR into KS cells showed that only NF-AT1 and NF-AT2 were activated by vGPCR." ?g. }
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- _5 value "Cotransfection of Jurkat cells with vGPCR and an NF-AT luciferase reporter plasmid showed that vGPCR activated NF-AT in a dose-dependent fashion, as judged by NF-AT luciferase reporter gene expression. The activation was calcineurin dependent because it was suppressed by cyclosporine A (CSA), a highly specific calcineurin inhibitor. Cotransfected expression constructs for NF-AT1 and NF-AT2 with vGPCR into KS cells showed that only NF-AT1 and NF-AT2 were activated by vGPCR." provenance.