Matches in Nanopublications for { ?s ?p "DDI between Mefloquine and Voriconazole - Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of mefloquine by decreasing its metabolism. Additive QTc prolongation may also occur. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of mefloquine if voriconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00358_DB00582]"@en ?g. }
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- drugbank_resource:DB00358_DB00582 label "DDI between Mefloquine and Voriconazole - Voriconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of mefloquine by decreasing its metabolism. Additive QTc prolongation may also occur. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects of mefloquine if voriconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00358_DB00582]" assertion.