Matches in Nanopublications for { ?s ?p "DDI between Simvastatin and Saxagliptin - Simvastatin is a moderate inhibitor of CYP3A4 and increases AUC of saxagliptin by 12%. Exposure of the active metabolite decreased by 2%. However, these changes in pharmacokinetics are not clinical significant."@en ?g. }
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- drugbank_resource:DB00641_DB06335 title "DDI between Simvastatin and Saxagliptin - Simvastatin is a moderate inhibitor of CYP3A4 and increases AUC of saxagliptin by 12%. Exposure of the active metabolite decreased by 2%. However, these changes in pharmacokinetics are not clinical significant." assertion.