Matches in Nanopublications for { ?s ?p "Differentiation of human THP-1 cells into foam cells on treatment with 12-O-tetradecanoylphorbol 13-acetate (PMA) was observed in atherosclerotic lesions. When these THP-1 differentiated cells were subsequently treated with oxidized low density lipoprotein (Ox-LDL), it was observed that ABC1 (a key regulator of the efflux of cholesterol from macrophages) was highly regulated. At the end of fourth day of treatment with Ox-LDL the expression of ABC1 was increased by 10-folds when compared with control. This indicates that Ox-LDL up-regulates ABC1 in differentiated THP-1cells." ?g. }
Showing items 1 to 1 of
1
with 100 items per page.
- _3 value "Differentiation of human THP-1 cells into foam cells on treatment with 12-O-tetradecanoylphorbol 13-acetate (PMA) was observed in atherosclerotic lesions. When these THP-1 differentiated cells were subsequently treated with oxidized low density lipoprotein (Ox-LDL), it was observed that ABC1 (a key regulator of the efflux of cholesterol from macrophages) was highly regulated. At the end of fourth day of treatment with Ox-LDL the expression of ABC1 was increased by 10-folds when compared with control. This indicates that Ox-LDL up-regulates ABC1 in differentiated THP-1cells." provenance.