Matches in Nanopublications for { ?s ?p "Dominant-negative mutant. Induces increased number of binucleated cells, indicating defects in cytokinesis. Inhibits the transport of NPC1L1 to the plama membrane. Disrupts the trafficking of CDH1 to the plasma membrane and promotes accumulation of CDH1 in RAB11A endosomes in nonpolarized cells. Promotes mistargeting of CDH1 to the apical membrane in polarized cells." ?g. }
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- NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4._1 comment "Dominant-negative mutant. Induces increased number of binucleated cells, indicating defects in cytokinesis. Inhibits the transport of NPC1L1 to the plama membrane. Disrupts the trafficking of CDH1 to the plasma membrane and promotes accumulation of CDH1 in RAB11A endosomes in nonpolarized cells. Promotes mistargeting of CDH1 to the apical membrane in polarized cells." NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4.assertion.
- NX_P62491-2_MUTAGEN_25_25.RA1rD4_qnvEOgHuZETTH9gcPcMChGlUYRRujEk_Q6Fmqw._1 comment "Dominant-negative mutant. Induces increased number of binucleated cells, indicating defects in cytokinesis. Inhibits the transport of NPC1L1 to the plama membrane. Disrupts the trafficking of CDH1 to the plasma membrane and promotes accumulation of CDH1 in RAB11A endosomes in nonpolarized cells. Promotes mistargeting of CDH1 to the apical membrane in polarized cells." NX_P62491-2_MUTAGEN_25_25.RA1rD4_qnvEOgHuZETTH9gcPcMChGlUYRRujEk_Q6Fmqw.assertion.