Matches in Nanopublications for { ?s ?p "IL-6 promotes tumor growth and metastasis by up-regulating VEGF expression and VEGF-mediated angiogenesis, and is closely associated with disease status and outcome of gastric cancer[27,28]. Recent studies demonstrated that IL-6 induced VEGF expression and angiogenesis via Stat3 in multiple tumors[29-31] and gastric cancer[32]. Blocking Stat3 signaling pathway down-regulated VEGF promoter activity, and effectively abolished IL-6-induced VEGF expression and angiogenesis[33,34]. " ?g. }
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- _5 value "IL-6 promotes tumor growth and metastasis by up-regulating VEGF expression and VEGF-mediated angiogenesis, and is closely associated with disease status and outcome of gastric cancer[27,28]. Recent studies demonstrated that IL-6 induced VEGF expression and angiogenesis via Stat3 in multiple tumors[29-31] and gastric cancer[32]. Blocking Stat3 signaling pathway down-regulated VEGF promoter activity, and effectively abolished IL-6-induced VEGF expression and angiogenesis[33,34]. " provenance.