Matches in Nanopublications for { ?s ?p "Incubation of nuclear extracts from peripheral blood mononuclear cells with anti-CD23 plus CD28 demonstrated increased binding of NFKB to IL17 promoters with shifted bands in p50 and p65. But treatment with LY294002 and PTDC, inhibitors of PI3K and NFkB, completely blocked the NFkB binding activity in the IL-17 promoter, indicating that CD3 and CD28 induced the translocation of p50-NFkB and increased its binding with the IL-17 promoter." ?g. }
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- _3 value "Incubation of nuclear extracts from peripheral blood mononuclear cells with anti-CD23 plus CD28 demonstrated increased binding of NFKB to IL17 promoters with shifted bands in p50 and p65. But treatment with LY294002 and PTDC, inhibitors of PI3K and NFkB, completely blocked the NFkB binding activity in the IL-17 promoter, indicating that CD3 and CD28 induced the translocation of p50-NFkB and increased its binding with the IL-17 promoter." provenance.