Matches in Nanopublications for { ?s ?p "InsP3?To further characterize the role of NADPH oxidase activation in stimulating the production of H2O2 and increasing the sensitivity to InsP3-stimulated intracellular Ca21 release, studies were performed in HAEC transiently expressing Rac1N17, a dominant negative allele of Rac1 (18). When transfected cells were stimulated with NADPH, H2O2 production was significantly reduced in comparison with vector controls (Fig. 7A) at all three NADPH concentrations examined." ?g. }
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- _6 value "InsP3?To further characterize the role of NADPH oxidase activation in stimulating the production of H2O2 and increasing the sensitivity to InsP3-stimulated intracellular Ca21 release, studies were performed in HAEC transiently expressing Rac1N17, a dominant negative allele of Rac1 (18). When transfected cells were stimulated with NADPH, H2O2 production was significantly reduced in comparison with vector controls (Fig. 7A) at all three NADPH concentrations examined." provenance.