Matches in Nanopublications for { ?s ?p "Ovalbumin (OVA) inhalation in sensitized mice induced substantial cytokine release into Bronchoalveolar lavage fluid (BALF) as compared with untreated mice. MEK1/2 inhibitor, U0126 significantly reduced IL5 levels in BAL fluid in a dose-dependent manner. U0126 (30 mg/kg) also effectively blocked the OVA-induced ERK1 phosphorylation. These results suggest that OVA-induced upregulation of IL5 was mediated through MEK/ERK pathway." ?g. }
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- _4 value "Ovalbumin (OVA) inhalation in sensitized mice induced substantial cytokine release into Bronchoalveolar lavage fluid (BALF) as compared with untreated mice. MEK1/2 inhibitor, U0126 significantly reduced IL5 levels in BAL fluid in a dose-dependent manner. U0126 (30 mg/kg) also effectively blocked the OVA-induced ERK1 phosphorylation. These results suggest that OVA-induced upregulation of IL5 was mediated through MEK/ERK pathway." provenance.
- _4 value "Ovalbumin (OVA) inhalation in sensitized mice induced substantial cytokine release into Bronchoalveolar lavage fluid (BALF) as compared with untreated mice. MEK1/2 inhibitor, U0126 significantly reduced IL5 levels in BAL fluid in a dose-dependent manner. U0126 (30 mg/kg) also effectively blocked the OVA-induced ERK1 phosphorylation. These results suggest that OVA-induced upregulation of IL5 was mediated through MEK/ERK pathway." provenance.