Matches in Nanopublications for { ?s ?p "PI-3K-PKB/Akt. Integrins can activate the serine/ threonine kinase PKB/Akt in a PI-3K-dependent manner through FAK and integrin-linked kinase (ILK) [66,67]. For activation, PKB/Akt requires phosphatidyl inositol-3 phosphate-dependent translocation to the cell membrane and phosphorylation at two sites, 308T and 473S [68]. Activation of PKB/Akt by VEGF [69], insulin [70], or angiopoietin-1 [71] only occurs under conditions of integrin-dependent adhesion [72]" ?g. }
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- _8 value "PI-3K-PKB/Akt. Integrins can activate the serine/ threonine kinase PKB/Akt in a PI-3K-dependent manner through FAK and integrin-linked kinase (ILK) [66,67]. For activation, PKB/Akt requires phosphatidyl inositol-3 phosphate-dependent translocation to the cell membrane and phosphorylation at two sites, 308T and 473S [68]. Activation of PKB/Akt by VEGF [69], insulin [70], or angiopoietin-1 [71] only occurs under conditions of integrin-dependent adhesion [72]" provenance.
- _8 value "PI-3K-PKB/Akt. Integrins can activate the serine/ threonine kinase PKB/Akt in a PI-3K-dependent manner through FAK and integrin-linked kinase (ILK) [66,67]. For activation, PKB/Akt requires phosphatidyl inositol-3 phosphate-dependent translocation to the cell membrane and phosphorylation at two sites, 308T and 473S [68]. Activation of PKB/Akt by VEGF [69], insulin [70], or angiopoietin-1 [71] only occurs under conditions of integrin-dependent adhesion [72]" provenance.
- _5 value "PI-3K-PKB/Akt. Integrins can activate the serine/ threonine kinase PKB/Akt in a PI-3K-dependent manner through FAK and integrin-linked kinase (ILK) [66,67]. For activation, PKB/Akt requires phosphatidyl inositol-3 phosphate-dependent translocation to the cell membrane and phosphorylation at two sites, 308T and 473S [68]. Activation of PKB/Akt by VEGF [69], insulin [70], or angiopoietin-1 [71] only occurs under conditions of integrin-dependent adhesion [72]" provenance.