Matches in Nanopublications for { ?s ?p "SC-514, a selective inhibitor of IKK2 reduced the level of translocation of p65 into the nucleus in IL-1beta treated Rheumatoid arthritic synovial fibroblast. EMSA and Western analysis revealed a reduction in the level of nuclease p65 in SC-514 treated cells, by 60 minutes post IL-1beta stimulation. By 90 minutes the SC-514 treated RASF cells demonstrated little nuclear staining compared with untreated cells suggesting that IKK2 is involved in the nuclear translocation of p65" ?g. }
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- _6 value "SC-514, a selective inhibitor of IKK2 reduced the level of translocation of p65 into the nucleus in IL-1beta treated Rheumatoid arthritic synovial fibroblast. EMSA and Western analysis revealed a reduction in the level of nuclease p65 in SC-514 treated cells, by 60 minutes post IL-1beta stimulation. By 90 minutes the SC-514 treated RASF cells demonstrated little nuclear staining compared with untreated cells suggesting that IKK2 is involved in the nuclear translocation of p65" provenance.
- _6 value "SC-514, a selective inhibitor of IKK2 reduced the level of translocation of p65 into the nucleus in IL-1beta treated Rheumatoid arthritic synovial fibroblast. EMSA and Western analysis revealed a reduction in the level of nuclease p65 in SC-514 treated cells, by 60 minutes post IL-1beta stimulation. By 90 minutes the SC-514 treated RASF cells demonstrated little nuclear staining compared with untreated cells suggesting that IKK2 is involved in the nuclear translocation of p65" provenance.