Matches in Nanopublications for { ?s ?p "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." ?g. }
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- _3 value "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." provenance.
- _3 value "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." provenance.
- _3 value "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." provenance.
- _3 value "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." provenance.
- _3 value "The AAV-expressing ribozyme decreased SOD2 mRNA and protein levels by as much as 85%, increased cellular superoxide, reduced mitochondrial membrane potential, and culminated in the death of infected cell lines by apoptosis without significantly altering complex I and III activity, although adenosine triphosphate (ATP) synthesis is markedly reduced resulting in optic neuropathy." provenance.