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Matches in Nanopublications for { ?s ?p "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." ?g. }

• _4 value "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." provenance.
• _4 value "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." provenance.
• _4 value "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." provenance.
• _4 value "These cells are said to display a 'contractile/ quiescent' phenotype (Thyberg, 1998; Regan et al., 2000). In contrast, during development, or in response to cardiovascular stresses in the adult, VSMC and VEC undergo a process of phenotypic modulation that results in the development of cells with migratory and proliferative phenotypes. Such 'synthetic/ activated' VSMC and VEC are no longer contractile and become sensitive to the growth-promoting and chemoattractant influences of plasma- and cell-derived factors (e.g., platelet-derived growth factor) (Thyberg, 1998; Regan et al., 2000). Although PDE1A and PDE1B enzymes selectively hydrolyze cGMP, PDE1C variants hydrolyze both cAMP and cGMP with high affinity (Zhao et al., 1997)." provenance.