Matches in Nanopublications for { ?s ?p "These reporter constructs were transiently transfected into K562 cells with or without pSG5/FKLF. Luciferase activities driven by the HS2 and six different promoters are shown in Fig. 9. The expected gamma gene promoter activation by FKLF was observed; in contrast, FKLF failed to activate the GATA-1 promoter (P = 0.14) in spite of the fact that it carries three CACCC elements and one potential Sp1-binding site (Fig. 8). FKLF could not significantly activate the FC promoter (P = 0.20), although it has two Sp1-binding sites. Similarly, there was no significant activation of GPB or PBGD promoters by FKLF (P = 0.15 or 0.09, respectively). The ALAS promoter carrying two CACCC elements was slightly activated by FKLF (P = 0.03; Fig. 9)." ?g. }
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- _4 value "These reporter constructs were transiently transfected into K562 cells with or without pSG5/FKLF. Luciferase activities driven by the HS2 and six different promoters are shown in Fig. 9. The expected gamma gene promoter activation by FKLF was observed; in contrast, FKLF failed to activate the GATA-1 promoter (P = 0.14) in spite of the fact that it carries three CACCC elements and one potential Sp1-binding site (Fig. 8). FKLF could not significantly activate the FC promoter (P = 0.20), although it has two Sp1-binding sites. Similarly, there was no significant activation of GPB or PBGD promoters by FKLF (P = 0.15 or 0.09, respectively). The ALAS promoter carrying two CACCC elements was slightly activated by FKLF (P = 0.03; Fig. 9)." provenance.