Matches in Nanopublications for { ?s ?p "This redundancy in function will be an important consideration in planning VEGF-specific anti-angiogenic therapies to induce regression of tumour blood vessels.Very little is known about the final step in the angiogenic process, in which vascular sprouts fuse with other sprouts to form loops and circulate the blood into the newly vascularized area (FIG. 2e). Tumours express various pro-angiogenic factors (FIG. 2).Although FGF (fibroblast growth factor) was the first to be discovered,VEGFA is perhaps the most ubiquitous. As well as VEGFA, other VEGF-family members are produced by human tumours, including VEGFC and VEGFD, which both bind to VEGF receptor-2 (VEGFR2) and activate many of the same pathways as VEGFA31." ?g. }
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- _5 value "This redundancy in function will be an important consideration in planning VEGF-specific anti-angiogenic therapies to induce regression of tumour blood vessels.Very little is known about the final step in the angiogenic process, in which vascular sprouts fuse with other sprouts to form loops and circulate the blood into the newly vascularized area (FIG. 2e). Tumours express various pro-angiogenic factors (FIG. 2).Although FGF (fibroblast growth factor) was the first to be discovered,VEGFA is perhaps the most ubiquitous. As well as VEGFA, other VEGF-family members are produced by human tumours, including VEGFC and VEGFD, which both bind to VEGF receptor-2 (VEGFR2) and activate many of the same pathways as VEGFA31." provenance.
- _5 value "This redundancy in function will be an important consideration in planning VEGF-specific anti-angiogenic therapies to induce regression of tumour blood vessels.Very little is known about the final step in the angiogenic process, in which vascular sprouts fuse with other sprouts to form loops and circulate the blood into the newly vascularized area (FIG. 2e). Tumours express various pro-angiogenic factors (FIG. 2).Although FGF (fibroblast growth factor) was the first to be discovered,VEGFA is perhaps the most ubiquitous. As well as VEGFA, other VEGF-family members are produced by human tumours, including VEGFC and VEGFD, which both bind to VEGF receptor-2 (VEGFR2) and activate many of the same pathways as VEGFA31." provenance.