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Matches in Nanopublications for { ?s ?p "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." ?g. }

• _7 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.
• _5 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.
• _7 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.
• _5 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.
• _5 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.
• _5 value "To test whether pRb is required for MyoD to activate the MEF2C TAD, we transfected Rb-/- fibroblasts with the Gal4-MEF2C fusion protein either alone or with MyoD and E12, in either the absence or the presence of exogenous pRb. When expressed alone, MyoD+E12 did not significantly stimulate Gal4-MEF2C function in these cells (Figure 3c, column 4). Similarly, the expression of pRb alone did not affect the activity of Gal4-MEF2C (Figure 3c, column 5); but, the combined expression of MyoD+E12 and pRb led to a 45-fold increase in the activity of Gal4-MEF2C (Figure 3c, column 6). These findings indicate that MyoDmediated activation of the MEF2C TAD requires pRb." provenance.