Matches in Nanopublications for { ?s ?p "We have shown previously that NHEK senescence arises in part through hydrogen peroxide (H2O2) accumulation. This accumulation was shown to result from an activation of NF-nB and ensuing up-regulation of MnSOD, responsible for the dismutation of O2 to H2O2. Without any coup- regulation of downstream H2O2-degrading enzymes, this leads to H2O2 accumulation (23)." ?g. }
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- _4 value "We have shown previously that NHEK senescence arises in part through hydrogen peroxide (H2O2) accumulation. This accumulation was shown to result from an activation of NF-nB and ensuing up-regulation of MnSOD, responsible for the dismutation of O2 to H2O2. Without any coup- regulation of downstream H2O2-degrading enzymes, this leads to H2O2 accumulation (23)." provenance.
- _4 value "We have shown previously that NHEK senescence arises in part through hydrogen peroxide (H2O2) accumulation. This accumulation was shown to result from an activation of NF-nB and ensuing up-regulation of MnSOD, responsible for the dismutation of O2 to H2O2. Without any coup- regulation of downstream H2O2-degrading enzymes, this leads to H2O2 accumulation (23)." provenance.