Matches in Nanopublications for { ?s ?p "When WR19L was transformed with CD47, the transformants, after induction of apoptosis, could be phagocytosed by BAM3. Masking of the phosphatidylserine exposed on apoptotic thymocytes inhibited the engulfment, whereas the anti-SHPS-1 mAb inhibited not only the engulfment, but also the binding of apoptotic cells to phagocytes. These results indicate that macrophages require CD47 and phosphatidylserine on apoptotic cells for engulfment, and suggest that the interaction between CD47 and SHPS1 works as a tethering step in the phagocytosis." ?g. }
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- _5 value "When WR19L was transformed with CD47, the transformants, after induction of apoptosis, could be phagocytosed by BAM3. Masking of the phosphatidylserine exposed on apoptotic thymocytes inhibited the engulfment, whereas the anti-SHPS-1 mAb inhibited not only the engulfment, but also the binding of apoptotic cells to phagocytes. These results indicate that macrophages require CD47 and phosphatidylserine on apoptotic cells for engulfment, and suggest that the interaction between CD47 and SHPS1 works as a tethering step in the phagocytosis." provenance.
- _5 value "When WR19L was transformed with CD47, the transformants, after induction of apoptosis, could be phagocytosed by BAM3. Masking of the phosphatidylserine exposed on apoptotic thymocytes inhibited the engulfment, whereas the anti-SHPS-1 mAb inhibited not only the engulfment, but also the binding of apoptotic cells to phagocytes. These results indicate that macrophages require CD47 and phosphatidylserine on apoptotic cells for engulfment, and suggest that the interaction between CD47 and SHPS1 works as a tethering step in the phagocytosis." provenance.