Matches in Nanopublications for { ?s <http://www.w3.org/ns/prov#value> ?o ?g. }
- _7 value "In this paper, we present a comprehensive pathway map of EGFR signaling and other related pathways." provenance.
- _6 value "In this paper, we present a comprehensive pathway map of EGFR signaling and other related pathways." provenance.
- _6 value "In this paper, we present a comprehensive pathway map of EGFR signaling and other related pathways." provenance.
- _7 value "S1P1=EDG1" provenance.
- _7 value "S1P3=EDG3 S1P2=EDG5" provenance.
- _6 value "VEGFR-1 and VEGFR-2 mRNA was identified in a number of breast cancer cell lines including T-47D, MCF7, MDA-MB-453, and MDA-MB-231, and these cancer cells were shown to respond to VEGF.85,86 VEGF stimulation increased the invasiveness of T-47D cells in the presence of fibronectin.85 ERK-1 and -2 were activated in response to VEGF in T-47D cells; PI3-K and its downstream target Akt were also activated. Since T-47D cells secrete VEGF87 it is likely that an autocrine VEGF loop exists within these cells. PI3-K activation has often been implicated in cellular invasion88 and may be the signalling mechanism in T-47D cells that mediates VEGF-induced cell invasion." provenance.
- _6 value "VEGFR-1 and VEGFR-2 mRNA was identified in a number of breast cancer cell lines including T-47D, MCF7, MDA-MB-453, and MDA-MB-231, and these cancer cells were shown to respond to VEGF.85,86 VEGF stimulation increased the invasiveness of T-47D cells in the presence of fibronectin.85 ERK-1 and -2 were activated in response to VEGF in T-47D cells; PI3-K and its downstream target Akt were also activated. Since T-47D cells secrete VEGF87 it is likely that an autocrine VEGF loop exists within these cells. PI3-K activation has often been implicated in cellular invasion88 and may be the signalling mechanism in T-47D cells that mediates VEGF-induced cell invasion." provenance.
- _5 value "This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol." provenance.
- _4 value "Human serum was fractionated over an IGFBP3 affinity column, and a 70-kD protein was eluted, sequenced, and identified (through database searching and Western immunoblot) as human TF. Biosensor interaction analysis confirmed that this interaction is specific and sensitive, with a high association rate similar to that of IGF1 (147440), and suggested that binding occurs in the vicinity of the IGFBP3 nuclear localization site. TF treatment blocked IGFBP3-induced cell proliferation in bladder smooth muscle cells and IGFBP3-induced apoptosis in prostate cancer cells." provenance.
- _4 value "CD-36, a second scavenger protein, also found in caveolae, has an weaker effect on cholesterol efflux" provenance.
- _4 value "VLDL particles contain apoB100 and apoCs with or without apoE IDLs contain apoB100 and apoE but not apoCs LDLs contain only apoB100" provenance.
- _4 value "VLDL particles contain apoB100 and apoCs with or without apoE IDLs contain apoB100 and apoE but not apoCs LDLs contain only apoB100" provenance.
- _4 value "absence of Abca1 results in almost complete absence of HDL and dramatic cellular cholesterol accumulation, particularly in the lungs" provenance.
- _4 value "absence of Pltp had reduced HDL levels" provenance.
- _6 value "because of the dominating role of apoC2 as cofactor for Lpl acitivity, the effects of congenital apoC2 deficiency in human plasma mimic those of Lpl deficiency" provenance.
- _3 value "comparison of the composition of IDL with that of the LDL indicates that this conversion involves the loss of 80-90% of IDL triacylglycerol, some phospholipid, and the dissociation of remaining apoE IDL free cholesterol content is the same as that in VLDL while cholesteryl ester is increased in LDL % as a result of the activity of cholesteryl ester transfer protein, CETP, that exchanges apoB-associated triacylglycerol for apoA1-associated cholesteryl esters" provenance.
- _5 value "in adipocytes, fasting is associated with the synthesis of Lpl molecules whose N-linked polysaccharide chains retain an unmodified high-mannose structure in the fed state, these chains are modified by mannose trimming, and the addition of glucose, hexosamine and sialic acid units the high mannose form of Lpl has low specific activity and is retained within the adipocyte the modified form is actively secreted insulin levels are an important determinant of Lpl processing" provenance.
- _4 value "in apoa1 deficiency, no HDL is present" provenance.
- _5 value "mature Lpl contains several polysaccharide chains, which are required for effective Lpl secretion unesterified fatty acids and lysophosphatidylcholine increase the rate of Lpl secretion from adipocytes" provenance.
- _5 value "monoacylglycerols are effective lysogens, they inhibit Lpl activity monoacylglycerols do not bind to albumin, but are taken up rapidly by cells Lpl also generate lysophospholipids these are effective lysogens but unlike monoacylglycerols, they form stable complexes with albumin" provenance.
- _4 value "most alpha HDL particles, unlike prebeta and discoidal-HDL, include A2 as well as apoa1 evidence recently obtained suggests that these are a product of the fusion of apoA1-only and apoA2-only HDL particles this fusion could be mediated locally by the lysophosphatidylcholine formed in the LCAT reaction apoa2 has been considered an inhibitor of the LCAT reaction, and thus indirectly, of reverse cholesterol transport" provenance.
- _4 value "note, PSOAT reaction is [Phosphatidylcholine + Sterol <=> 1-Acylglycerophosphocholine + Steryl ester] LCAT can also hydrolyze short-chain lipid esters this reaction is independent of the presence of apoa1, consistent with the view that the apoprotein may be needed to align the enzyme and its substrates at a phospholipid-water interface in LCAT deficiency only lipid-poor and discoidal HDL particles are present" provenance.
- _4 value "Finally, leptin prevented the induction of CRF synthesis in the PVN and the activation of the PVN CRF neurons observed in food-deprived ob/ob mice and hindered the elevation of arcuate nucleus neuropeptide Y synthesis in ob/ob mice. is translated to Inhibition of CRH (Homo sapiens) Gene Expression by LEP (Homo sapiens) Protein" provenance.
- _4 value "In summary, the present study demonstrates that insulin sensitizers have different effects on MMP-1 expression, and troglitazone stimulates MMP-1 mRNA expression and protein synthesis at the pharmacological concentrations, but inhibits MMP-1 synthesis at higher doses. is translated to Activation of MMP1 (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _4 value "In vitro studies, using isolated rat aorta rings, revealed that troglitazone (4.5 to 45 microM) increases PGI2 production by 31 and 70%, respectively. is translated to Activation of PTGIS (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _7 value "J Leukoc Biol 2003 Mar 73(3) 363-8 (ResnetDB) An inhibitor of PKC, GF 109203X inhibited EGF-mediated suppression of TNF-alpha-induced accumulation of p53, p21 and induction of apoptosis. is translated to Activation of CDKN1A (Homo sapiens) Gene Expression by TNF (Homo sapiens) Protein" provenance.
- _5 value "Pioglitazone (0.1 to 10 micromol/L) significantly enhanced cytokine-induced expression of iNOS and NO production in a dose-dependent manner in rat VSMCs, but 15-deoxy-Delta(12,14)-prostaglandin J2 (up to 10 micromol/L), a native peroxisome proliferator-activated receptor-gamma ligand, showed no effect. is translated to Activation of NOS2A (Homo sapiens) Gene Expression by Pioglitazone" provenance.
- _4 value "Pioglitazone (0.1 to 10 micromol/L) significantly enhanced cytokine-induced expression of iNOS and NO production in a dose-dependent manner in rat VSMCs, but 15-deoxy-Delta(12,14)-prostaglandin J2 (up to 10 micromol/L), a native peroxisome proliferator-activated receptor-gamma ligand, showed no effect. is translated to Activation of NOS2A (Homo sapiens) Gene Expression by Pioglitazone" provenance.
- _4 value "Rosiglitazone increased carboxypeptidase B expression in both lep/lep and normal mice suggesting that this might be an independent effect of rosiglitazone that contributes to improved insulin processing. is translated to Activation of CPB1 (Homo sapiens) Gene Expression by Rosiglitazone" provenance.
- _4 value "Rosiglitazone increased carboxypeptidase B expression in both lep/lep and normal mice suggesting that this might be an independent effect of rosiglitazone that contributes to improved insulin processing. is translated to Activation of CPB1 (Homo sapiens) Gene Expression by Rosiglitazone" provenance.
- _4 value "The experiments reported in this study establish that the insulin-sensitizing agent pioglitazone up-regulates expression of the aFABP gene through an element located within a region of DNA responsible for tissue-specific and differentiation-dependent expression of the gene. is translated to Activation of FABP4 (Homo sapiens) Gene Expression by Pioglitazone" provenance.
- _4 value "Troglitazone also dramatically increased A-FABP expression in cultured MCs. is translated to Activation of FABP4 (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _4 value "Troglitazone treatment increased expression of two cyclin-dependent kinase inhibitors, p21(WAF1/CIP1) and p16(INK4), and reduced cyclin D1 expression, consistent with G1 arrest. is translated to Activation of CDKN2A (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _4 value "Troglitazone treatment increased expression of two cyclin-dependent kinase inhibitors, p21(WAF1/CIP1) and p16(INK4), and reduced cyclin D1 expression, consistent with G1 arrest. is translated to Activation of CDKN2A (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _4 value "Troglitazone treatment increased expression of two cyclin-dependent kinase inhibitors, p21(WAF1/CIP1) and p16(INK4), and reduced cyclin D1 expression, consistent with G1 arrest. is translated to Activation of CDKN2A (Homo sapiens) Gene Expression by Troglitazone" provenance.
- _5 value "Not Available" provenance.
- _6 value "Not Available" provenance.
- _6 value "Not Available" provenance.
- _6 value "Not Available" provenance.
- _5 value "Not Available" provenance.
- _5 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _5 value "Not Available" provenance.
- _8 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _4 value "Page 444 Bile acids inhibit the expression of the cyp8b1 gene (encodes the sterol 12alpha-hydroxylase in parallel with the cyp7a. Suppression of cyp8b1 gene expression is likely mediated through SHP, as LRH-1 is also required for cyp8b1 promoter activity." provenance.
- _5 value "Table 2 Transcription factors shown to have functional interaction with the cyp7a gene promotor" provenance.
- _4 value "Insulin-induced SREBP-1c expression and activity results in downregulation of PEPCK gene expression and upregulation of GK gene transcription (40-42), resulting in a decreased glucose production and an increased glucose uptake." provenance.
- _5 value "Entrez Gene summary: Rat: SUMMARY: major neurotransmitter-degrading enzyme in the CNS; degrades biogenic monoamines in the brain [RGD] Human: The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. OMIM summary: (summary is not available from this source)" provenance.
- _6 value "Dehydration of 5-HpETE to leukotriene A4. In the second step, 5-lipoxygenase converts 5-HpETE to an allylic epoxide, leukotriene A4." provenance.
- _5 value "Chapter 12 - Synthesis followed by translation and secretion of IL2 lead to T-cell activation in an autocrine manner." provenance.
- _6 value "Chapter 14: Only the membranes from activated Th cells induce B-cell proliferation, suggesting that one or more molecules expresed on the membrane of an activated Th cell engage the receptors on the B-cell to provide contact dependent help. Likely mediators of such contact-dependent help are CD40, which is expressed on the membrane of all B-cells, and its newly discovered ligand, CD40L, which is expressed on the membrane of activated Th cells." provenance.
- _6 value "Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, {600664}, or IKBKB, {603258}) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex." provenance.
- _6 value "Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, {600664}, or IKBKB, {603258}) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex." provenance.
- _6 value "Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, {600664}, or IKBKB, {603258}) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex." provenance.
- _5 value "NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]" provenance.
- _5 value "HORMONES IN SKELETAL MUSCLE HYPERTROPHY Hormones are chemicals which organs secrete to initiate or regulate the activity of an organ or group of cells in another part of the body. It should be noted that hormone function is decidedly affected by nutritional status, foodstuff intake and lifestyle factors such as stress, sleep, and general health. The following hormones are of special interest in skeletal muscle hypertrophy. GROWTH HORMONE Growth hormone (GH) is a peptide hormone that stimulates IGF in skeletal muscle, promoting satellite cell activation, proliferation and differentiation (9). However, the observed hypertrophic effects from the additional administration of GH, investigated in GH-treated groups doing resistance exercise, may be less credited with contractile protein increase and more attributable to fluid retention and accumulation of connective tissue (9)." provenance.
- _4 value "INSULIN-LIKE GROWTH FACTOR IGF is a hormone that is secreted by skeletal muscle. It regulates insulin metabolism and stimulates protein synthesis. There are two forms, IGF-I, which causes proliferation and differentiation of satellite cells, and IGF-II, which is responsible for proliferation of satellite cells. In response to progressive overload resistance exercise, IGF-I levels are substantially elevated, resulting in skeletal muscle hypertrophy (7)." provenance.
- _3 value "TESTOSTERONE Testosterone is an androgen, or a male sex hormone. The primary physiological role of androgens are to promote the growth and development of male organs and characteristics. Testosterone affects the nervous system, skeletal muscle, bone marrow, skin, hair and the sex organs. With skeletal muscle, testosterone, which is produced in significantly greater amounts in males, has an anabolic (muscle building) effect. This contributes to the gender differences observed in body weight and composition between men and women. Testosterone increases protein synthesis, which induces hypertrophy (11)." provenance.
- _6 value "The sentence (Jubilant) Abeta(25-35) fibrils induced activation of Lyn, Syk, Pyk2 and focal adhesion kinase. is translated to Activation of PTK2 (Homo sapiens) Protein -> PTK2 (Homo sapiens) Protein phosphorylated at ? by APP (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 11160388 APP (Homo sapiens) Protein PTK2 (Homo sapiens) Protein -> PTK2 (Homo sapiens) Protein phosphorylated at ?" provenance.
- _6 value "The sentence (Jubilant) EGF activated Akt via PI3K phosphorylation. is translated to Activation of PI3K Family Hs -> PI3K Family Hs phosphorylated at ? by EGF (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 10197612 EGF (Homo sapiens) Protein PI3K Family Hs -> PI3K Family Hs phosphorylated at ?" provenance.
- _6 value "The sentence (Jubilant) Pi3k (an activator of Akt) inhibitor LY294002 partially blocked CT105 induced TNF-alpha production. is translated to Activation of TNF (Homo sapiens) Protein by AKT family Hs The following edits have been made already none Links Doc Sourcerer for 12606779 TNF (Homo sapiens) Protein AKT family Hs" provenance.
- _7 value "The sentence (Jubilant) TGFB induces phosphorylation of SMAD2 is inhibited by SB-431542 , an inhibitor of ALK4, ALK5 and ALK7. is translated to Complex of ACVR1B (Homo sapiens) Protein and TGFB1 (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 12065756 ACVR1B (Homo sapiens) Protein TGFB1 (Homo sapiens) Protein" provenance.
- _6 value "The sentence (ResnetDB) Moreover, treatment of wild-type cells with tyrphostin AG1007, which inhibits both pp60(c-src) and FAK activity, induced accumulation of tensin in peripheral focal adhesions. is translated to Activation of TNS (Homo sapiens) Gene Expression by PTK2 (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 11493667 TNS (Homo sapiens) Gene Expression PTK2 (Homo sapiens) Protein" provenance.
- _6 value "The sentence (ResnetDB) Moreover, treatment of wild-type cells with tyrphostin AG1007, which inhibits both pp60(c-src) and FAK activity, induced accumulation of tensin in peripheral focal adhesions. is translated to Activation of TNS (Homo sapiens) Gene Expression by PTK2 (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 11493667 TNS (Homo sapiens) Gene Expression PTK2 (Homo sapiens) Protein" provenance.
- _6 value "The sentence (ResnetDB) We show here that E2F1 induces PPAR gamma transcription during clonal expansion, whereas E2F4 represses PPARg amma expression during terminal adipocyte differentiation. is translated to Activation of PPARG (Homo sapiens) Gene Expression by E2F1 (Homo sapiens) Protein The following edits have been made already none Links Doc Sourcerer for 12110166 PPARG (Homo sapiens) Gene Expression E2F1 (Homo sapiens) Protein" provenance.
- _6 value "Entrez Gene summary: Rat: SUMMARY: may mediate a delay in G2 to M cell cycle progression; may induce DNA repair [RGD] ... Human: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. OMIM summary: (summary is not available from this source)" provenance.
- _5 value "Not Available" provenance.
- _5 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _7 value "Not Available" provenance.
- _3 value "Not Available" provenance.
- _5 value "this effect is mediated through E2 via the phosphorylation of extracellular-regulated kinase 1 and 2 (ERK1/2), prominent members of the mitogen-activated protein kinase (MAPK) pathway. Furthermore, we show that the activation of MAPK-signaling pathway and the enhancement of the sAPP release is independent of ERs" provenance.
- _6 value "4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one. 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol and NAD+ react to form 4-methylcholesta-8(9),24-dien-3-one, CO2, and NADH + H+. This reaction occurs in the endoplasmic reticulum, catalyzed by NSDHL (Caldas and Herman 2003). Defects in this enzyme are associated with CHILD syndrome (Congenital Hemidysplasia with Ichthyosiform nevus and Limb Defects) (Konig et al. 2000), but cholesterol biosynthesis in cells and tissues from affected individuals has not been characterized. Instead, the mechanism and stoichiometry of the reaction are inferred from biochemical studies of partially purified rat enzyme (Rahimtula and Gaylor 1972)." provenance.
- _5 value "Entrez Gene summary: Human: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene." provenance.
- _6 value "TGF-a, and its receptor EGFR, are reported to be overexpressed in up to 50% of invasive breast cancers, and in most studies both are associated with increased proliferation" provenance.
- _5 value "Targeted inactivation of CREM leads to a complete block of mouse spermiogenesis." provenance.
- _5 value "VEGF has been shown to promote endothelial cell survival by inhibiting apoptosis pathways, upregulating antiapoptotic proteins such as BCL2 and survivin, and activating proteins such as focal adhesion kinase that maintain endothelial cell survival despite apoptotic stimuli" provenance.
- _4 value "VEGF is one of the most potent vascular permeabilizing agents known, with an effect that is 50,000 times greater than that of histamine VEGF increases permeability in a variety of vascular beds including those of the skin, peritoneal wall, mesentery, and diaphram" provenance.
- _5 value "VEGFR2 functions: endothelial cell proliferation, endothelial cell migration, endothelial cell survival, endothelial cell differentiation, nitric oxide production, vascular permeability, angiogenesis" provenance.
- _5 value "VEGFR3 functions: lymphatic endothelial cell proliferation, lymphatic endothelial cell migration, lymphangiogenesis" provenance.
- _7 value "endothelial cell proliferation appears to involve VEGFR2-mediated activation of the MAPKs Erk1 and Erk2 in addition to another member of the MAPK family, JNK/SAPK, as well as the protein kinase C pathway" provenance.
- _6 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _6 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _8 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _8 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _8 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _5 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _7 value "There was a concomitant glucose-dependent onset of expression of Protein Kinase C (PKC)-isoforms PKC-delta (2.5 +/- 0.3-fold), PKC-epsilon (2 +/- 0.2-fold) and PKC-zeta (1.8 +/- 0.2-fold), which reached a maximum after 12 h and was still visible during long-term culture. Induction of fibronectin expression was also obtained using the PKC-activating phorbolester" provenance.
- _5 value "The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol" provenance.
- _4 value "Not Available" provenance.
- _4 value "Not Available" provenance.
- _4 value "Not Available" provenance.
- _6 value "Not Available" provenance.
- _6 value "Not Available" provenance.
- _4 value "Not Available" provenance.
- _4 value "Not Available" provenance.