Matches in Nanopublications for { ?s <http://www.w3.org/ns/prov#value> ?o ?g. }
- _4 value "TABLE I Sema 3A regulates gene expression in PC12 cells and hippocampal neurons (PC12+SEMA3A and PC12+NGF columns)" provenance.
- _4 value "TABLE I Sema 3A regulates gene expression in PC12 cells and hippocampal neurons (PC12+SEMA3A and PC12+NGF columns)" provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table II. The MCF-7a genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table III. The MCF-7b genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table III. The MCF-7b genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table III. The MCF-7b genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table III. The MCF-7b genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table III. The MCF-7b genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table IV. The MRC-9 genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table IV. The MRC-9 genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table IV. The MRC-9 genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table IV. The MRC-9 genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _3 value "Table IV. The MRC-9 genomic response to H2O2 at 5 hours. Genes with a significant change in gene expression between treated and untreated samples in 2 independent experiments are listed." provenance.
- _4 value "Lastly, PV1 upregulation by PMA required the activation of Erk1/2 MAP kinase pathway and was protein kinase C independent" provenance.
- _8 value "Here we show that STAT3 is activated in the presence of active Notch, as well as the Notch effectors Hes1 and Hes5. Hes proteins associate with JAK2 and STAT3, and facilitate complex formation between JAK2 and STAT3, thus promoting STAT3 phosphorylation and activation. " provenance.
- _7 value "In neuroepithelial cells, expression of Notch?E increased, and treatment with L-685,458 decreased, the level of tyrosine phosphorylation of endogenous STAT3" provenance.
- _7 value "We found that HERP1 and HERP2, but not the proneural bHLH proteins (neurogenin 1 (Ngn1),Ngn2,Mash1 and NeuroD) or Id1, induced the phosphorylation of STAT3 (Supplementary Information, Fig. S3d and data not shown). Consistently, HERP1 and HERP2, but not Ngn1, Ngn2, Mash1, NeuroD or Id1, activated STAT-dependent APRE-luc expression (Supplementary Information, Fig. S3e and data not shown)" provenance.
- _7 value "We found that HERP1 and HERP2, but not the proneural bHLH proteins (neurogenin 1 (Ngn1),Ngn2,Mash1 and NeuroD) or Id1, induced the phosphorylation of STAT3 (Supplementary Information, Fig. S3d and data not shown). Consistently, HERP1 and HERP2, but not Ngn1, Ngn2, Mash1, NeuroD or Id1, activated STAT-dependent APRE-luc expression (Supplementary Information, Fig. S3e and data not shown)" provenance.
- _3 value "Using microarray analysis of VHL mutated and re-introduced cells, we found that one of the prolyl hydroxylases (PHD3) is coordinately expressed with known HIF target genes, while the other two family members (PHD1 and 2) did not respond to VHL." provenance.
- _8 value "Tbx3 is able to repress Nppa and Cx40 promoter activity and abolish the synergistic activation of the Nppa promoter by Tbx5 and Nkx2.5." provenance.
- _5 value "Shear stress, via G proteins (Gs), can activate several signal transduction pathways, including the phosphoinoside 3-kinase (PI3K) and adenylate cyclase (AC) pathways, leading to eNOS activation via phosphorylation of serine residues (S617 and S1179 for Akt, and S635 and S1179 for PKA), which promote eNOS activation." provenance.
- _5 value "E-cadherin down-regulation [immunohistochemically and western] correlated with the cytoplasmic localization of p120ctn. Similar cytoplasmic localization of p120ctn and growth factor [heregulin]-induced accumulation of tyrosine-phosphorylated p120ctn in the protrusive domain were observed in E-cadherin-deficient breast cancer cells." provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _3 value "table 1 - Gene regulation by glucose, ranked according to fold change, is compared with that by KCl-induced depolarization and with insulin treatment" provenance.
- _5 value "Phosphorylation of Tyr-783, which is essential for lipase activation, was observed in all stimulated cell types examined. " provenance.
- _3 value "BTC stimulated proliferation and migration of VSMCs" provenance.
- _5 value "Following depletion of both serum and Epo for 2 hours, p44/42 ERK (Phospho ERK1 (Thr202/Tyr204); phospho-ERK2 (Thr185/Tyr187)) remained active in H-ras.V12-transduced cells but not in the control cells. No difference was seen in the expression of total p44/42 ERK in the 2 populations of cells" provenance.
- _5 value "Following depletion of both serum and Epo for 2 hours, p44/42 ERK (Phospho ERK1 (Thr202/Tyr204); phospho-ERK2 (Thr185/Tyr187)) remained active in H-ras.V12-transduced cells but not in the control cells. No difference was seen in the expression of total p44/42 ERK in the 2 populations of cells" provenance.
- _5 value "Following depletion of both serum and Epo for 2 hours, p44/42 ERK (Phospho ERK1 (Thr202/Tyr204); phospho-ERK2 (Thr185/Tyr187)) remained active in H-ras.V12-transduced cells but not in the control cells. No difference was seen in the expression of total p44/42 ERK in the 2 populations of cells" provenance.
- _5 value "The related adhesion focal tyrosine kinase (RAFTK), also known as Pyk2, undergoes autophosphorylation upon its stimulation......First, upon stimulus, RAFTK trans-autophosphorylates Tyr402. Second, phosphorylated Tyr402 recruits and activates Src kinase that in turn phosphorylates RAFTK and enhances its kinase activity." provenance.
- _3 value "Our data suggest that up-regulation of SOCS2 in neuronal progenitor cells derived from the adult SVZ may regulate EPO enhanced neuronal differentiation" provenance.
- _5 value "from full text:Our data showed that phosphorylation of Pak1 Ser-199/204 was enhanced by DSCAM (Fig. 5B), whereas Pak1 phosphorylation induced by RacL61 was observed as a positive control." provenance.
- _7 value "PKC inhibition by chelerythrine chloride and myristoylated PKC pseudosubstrate, as well as PKC downregulation by PMA strongly reduce cytoskeleton-dependent ALCAM-mediated adhesion." provenance.
- _6 value "Activated, GTP-bound Cdc42, Rac1, and Rac2 bind to the p21-binding domain (PBD) of PAK1" provenance.
- _4 value "Histone deacetylase (HDAC) inhibitors inhibit the proliferation of transformed cells in vitro, restrain tumor growth in animals" provenance.
- _5 value "By using SHP-2 substrate-trapping mutants, we identified p190-B RhoGAP as a SHP-2 substrate. When dephosphorylated, p190-B RhoGAP has been shown to stimulate the activation of RhoA. During myogenesis, p190-B RhoGAP was tyrosyl dephosphorylated concomitant with the stimulation of SHP-2's phosphatase activity. These observations strongly suggest that SHP-2 dephosphorylates p190-B RhoGAP, leading to the activation of RhoA." provenance.
- _5 value "By using SHP-2 substrate-trapping mutants, we identified p190-B RhoGAP as a SHP-2 substrate. When dephosphorylated, p190-B RhoGAP has been shown to stimulate the activation of RhoA. During myogenesis, p190-B RhoGAP was tyrosyl dephosphorylated concomitant with the stimulation of SHP-2's phosphatase activity. These observations strongly suggest that SHP-2 dephosphorylates p190-B RhoGAP, leading to the activation of RhoA." provenance.
- _4 value "Finally, we show that the nuclear localization of ESE-1 protein induces apoptosis in nontransformed mammary epithelial cells via a transcription-dependent mechanism. Together, our studies reveal two distinct ESE-1 functions, apoptosis and transformation, where the ESE-1 transcription activation domain contributes to apoptosis and the SAR domain mediates transformation via a novel nonnuclear, nontranscriptional mechanism." provenance.
- _5 value "Here we demonstrate that Ras downregulates RhoB expression by a phosphatidylinositol 3-kinase (PI3K)- and Akt- but not Mek-dependent mechanism." provenance.
- _2 value "glucosamine (5 x 10(-3) and 10(-2) M) reduced basal and insulin-stimulated glucose uptake" provenance.
- _4 value "over-expression of GFAT in skeletal muscle of transgenic mice and rat fibroblasts causes insulin resistance [10, 11] and increased activity of GFAT has been noted in muscle and other tissues of insulin resistant diabetic animals and humans" provenance.
- _4 value "Moreover, IL-1beta has been found to increase iron efflux from C6 cells, suggesting that both proteins may play a crucial role in iron homeostasis in pathological brain conditions, such as inflammatory and/or neurodegenerative diseases." provenance.
- _4 value "higher expression level of CP and FP was also confirmed by Western blotting" provenance.
- _5 value "PhosphoElm data from PMID 15212693" provenance.
- _3 value "Our analysis confirmed previous findings on genes whose expression is regulated by oxygen concentration but also identified new genes (e.g., CXCR4, claudin 3, CD24, tetranectin, Del-1, procollagen lysyl hydroxylase 1 and 2) which are transcriptionally upregulated in hypoxic conditions." provenance.
- _3 value "Our analysis confirmed previous findings on genes whose expression is regulated by oxygen concentration but also identified new genes (e.g., CXCR4, claudin 3, CD24, tetranectin, Del-1, procollagen lysyl hydroxylase 1 and 2) which are transcriptionally upregulated in hypoxic conditions." provenance.
- _3 value "Our analysis confirmed previous findings on genes whose expression is regulated by oxygen concentration but also identified new genes (e.g., CXCR4, claudin 3, CD24, tetranectin, Del-1, procollagen lysyl hydroxylase 1 and 2) which are transcriptionally upregulated in hypoxic conditions." provenance.
- _3 value "Our analysis confirmed previous findings on genes whose expression is regulated by oxygen concentration but also identified new genes (e.g., CXCR4, claudin 3, CD24, tetranectin, Del-1, procollagen lysyl hydroxylase 1 and 2) which are transcriptionally upregulated in hypoxic conditions." provenance.
- _4 value "It was reported previously that 1,25[OH]2VD3 induced cell cycle arrest not only at the G0/G1 phase but also at the G2/M phase." provenance.
- _6 value "The addition of 10(-8) to 10(-6) M 1,25[OH]2VD3 to cultured normal human keratinocytes enhanced the expression of Myt1 mRNA preceding Wee1 mRNA; 10(-6) M 1,25[OH]2VD3 unregulated Myt1 mRNA from 6 h to 24 h and Wee1 mRNA from 12 to 48 h." provenance.
- _4 value "PAR bZip-deficient mice show decreased brain levels of PLP, serotonin, and dopamine, and such changes have previously been reported to cause epilepsies in other systems." provenance.
- _3 value "However, upon treatment of monocytes with oxidized lowdensity lipoprotein, CCR2 expression is decreased dramatically (Han et al. 1998 and 2000)." provenance.
- _3 value "Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factorkappaB and activator protein-1." provenance.
- _4 value "Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factorkappaB and activator protein-1." provenance.
- _3 value "Androgen withdrawal (DCC-serum), in the presence of antiandrogen Casodex or in AR-negative prostate cancer cells (PC3 and DU145), vitamin D(3) failed to regulate FACL3/ACS3 expression. The upregulation of FACL3/ACS3 expression by vitamin D(3) was recovered by the addition of DHT in DCC-serum medium. Western blot analysis showed that the expression of androgen receptor (AR) protein was consistent with vitamin D(3) regulation of FACL3/ACS3 expression" provenance.
- _3 value "the upregulation of FACL3/ACS3 expression by vitamin D(3) is through an androgen/AR-mediated pathway" provenance.
- _4 value "IGFBP-3 inhibits the binding of IGF-I to its receptor and thereby inhibits IGF-I-stimulated growth." provenance.
- _7 value "IGFBP-3 stimulated TGF-betaRII-dependent serine phosphorylation (activation) of both TGF-betaRI and of its primary substrate, Smad2(Ser465/467)." provenance.
- _7 value "IGFBP-3 stimulated TGF-betaRII-dependent serine phosphorylation (activation) of both TGF-betaRI and of its primary substrate, Smad2(Ser465/467)." provenance.
- _5 value "IGFBP-3 stimulated TGF-betaRII-dependent serine phosphorylation (activation) of both TGF-betaRI and of its primary substrate, Smad2(Ser465/467)." provenance.
- _4 value "PDE4, rather than PDE3, appears to be responsible for modulating the amplitude and duration of the cAMP response to beta-agonists." provenance.
- _6 value "PDE4, rather than PDE3, appears to be responsible for modulating the amplitude and duration of the cAMP response to beta-agonists." provenance.
- _3 value "VEGF acts as a survival factor for endothelial cells through the inhibition of apoptosis" provenance.
- _4 value "VEGF gene expression is upregulated by a host of stimuli, including estrogen, nitric oxide and a variety of growth factors, such as fibroblast growth factor-4, PDGF, TNF-alpha, EGF, TGFbeta, keratinocyte growth factor, IL6, IL1B, and IGF1" provenance.
- _7 value "VEGF-C and VEGF-D bind a 3rd receptor, VEGFR3 (FLT4), through which they mediate lymphangiogenesis and also show some activity toward VEGFR2" provenance.
- _3 value "angiopoietin-1 and angiopoietin-2" provenance.
- _5 value "bevacizumab, a humanized monoclonal antibody directed at VEGF, is the most advanced in clinical trial development and has shown promising results in clinical trials" provenance.
- _3 value "cartilage-derived inhibitor CD59 complement fragment" provenance.