Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB00003_nanopub.RADK6_axMre05UcuSC9Fji4lf8ZaPT5DvrLjZ2AtwAoC4#assertion>. }
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- drugbank:DB00003 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00003 label "Dornase alfa [drugbank:DB00003]" assertion.
- drugbank:DB00003 seeAlso DB00003 assertion.
- drugbank:DB00003 seeAlso dornase-alfa.html assertion.
- drugbank:DB00003 seeAlso pulmozyme.htm assertion.
- drugbank:DB00003 identifier "drugbank:DB00003" assertion.
- drugbank:DB00003 description "Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA. In individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections. Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity." assertion.
- drugbank:DB00003 title "Dornase alfa" assertion.
- drugbank:DB00003 bio2rdf_vocabulary:identifier "DB00003" assertion.
- drugbank:DB00003 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00003 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00003" assertion.
- drugbank:DB00003 bio2rdf_vocabulary:x-identifiers.org DB00003 assertion.
- drugbank:DB00003 drugbank_vocabulary:drugbank-id "BIOD00001" assertion.
- drugbank:DB00003 drugbank_vocabulary:drugbank-id "BTD00001" assertion.
- drugbank:DB00003 drugbank_vocabulary:drugbank-id "DB00003" assertion.
- drugbank:DB00003 drugbank_vocabulary:x-cas cas:9003-98-9 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-ahfs ahfs:44:00 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-atc atc:R05CB13 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-dpd dpd:2046733 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-pharmgkb pharmgkb:PA10318 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-wikipedia wikipedia:Dornase_alfa assertion.
- drugbank:DB00003 drugbank_vocabulary:x-genbank genbank:M55983 assertion.
- drugbank:DB00003 drugbank_vocabulary:x-uniprot uniprot:P24855 assertion.