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- drugbank:DB00069 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00069 label "Interferon alfacon-1 [drugbank:DB00069]" assertion.
- drugbank:DB00069 seeAlso DB00069 assertion.
- drugbank:DB00069 seeAlso interferon-alfacon-1.html assertion.
- drugbank:DB00069 seeAlso infergen.htm assertion.
- drugbank:DB00069 identifier "drugbank:DB00069" assertion.
- drugbank:DB00069 description "Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the molecular construction, and a corresponding synthetic DNA sequence was constructed using chemical synthesis methodology. Interferon alfacon-1 differs from interferon alfa-2b at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of the amino acid positions. Interferon alfacon-1 is produced in Escherichia coli (E. coli) cells that have been genetically altered by insertion of a synthetically constructed sequence that codes for Interferon alfacon-1. Prior to final purification, Interferon alfacon-1 is allowed to oxidize to its native state, and its final purity is achieved by sequential passage over a series of chromatography columns. This protein has a molecular weight of 19,434 daltons." assertion.
- drugbank:DB00069 title "Interferon alfacon-1" assertion.
- drugbank:DB00069 bio2rdf_vocabulary:identifier "DB00069" assertion.
- drugbank:DB00069 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00069 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00069" assertion.
- drugbank:DB00069 bio2rdf_vocabulary:x-identifiers.org DB00069 assertion.
- drugbank:DB00069 drugbank_vocabulary:drugbank-id "BIOD00062" assertion.
- drugbank:DB00069 drugbank_vocabulary:drugbank-id "BTD00062" assertion.
- drugbank:DB00069 drugbank_vocabulary:drugbank-id "DB00069" assertion.
- drugbank:DB00069 drugbank_vocabulary:x-cas cas:118390-30-0 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-ahfs ahfs:10:00.00 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-atc atc:L03AB09 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-dpd dpd:2239832 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164749376 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-ndc ndc:0187-2007-06 assertion.
- drugbank:DB00069 drugbank_vocabulary:x-genbank genbank:J00207 assertion.