Nanopublications LDF server

Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB00264_nanopub.RAgbGZFaK6z0dmLKWMyKqh4mEpRiHGWg0lQKdr2T3mo4Q#assertion>. }

• drugbank:DB00264 type drugbank_vocabulary:Drug assertion.
• drugbank:DB00264 label "Metoprolol [drugbank:DB00264]" assertion.
• drugbank:DB00264 seeAlso DB00264 assertion.
• drugbank:DB00264 seeAlso metoprolol.html assertion.
• drugbank:DB00264 seeAlso metopxl.htm assertion.
• drugbank:DB00264 identifier "drugbank:DB00264" assertion.
• drugbank:DB00264 description "Metoprolol is a cardioselective β1-adrenergic blocking agent used for acute myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. It may also be used for supraventricular and tachyarrhythmias and prophylaxis for migraine headaches. Metoprolol is structurally similar to bisoprolol, acebutolol and atenolol in that it has two substituents in the <i>para</i> position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the <i>para</i> position. At low doses, metoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with higher doses. Unlike propranolol and pindolol, metoprolol does not exhibit membrane-stabilizing or intrinsic sympathomimetic activity. Membrane-stabilizing effects are only observed at doses much higher than those needed for β-adrenergic blocking activity. Metoprolol possesses a single chiral centre and is administered as a racemic mixture." assertion.
• drugbank:DB00264 title "Metoprolol" assertion.
• drugbank:DB00264 bio2rdf_vocabulary:identifier "DB00264" assertion.
• drugbank:DB00264 bio2rdf_vocabulary:namespace "drugbank" assertion.
• drugbank:DB00264 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00264" assertion.
• drugbank:DB00264 bio2rdf_vocabulary:x-identifiers.org DB00264 assertion.
• drugbank:DB00264 drugbank_vocabulary:drugbank-id "APRD00208" assertion.
• drugbank:DB00264 drugbank_vocabulary:drugbank-id "DB00264" assertion.
• drugbank:DB00264 drugbank_vocabulary:x-cas cas:37350-58-6 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-chemspider chemspider:4027 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-pubchemcompound pubchem.compound:4171 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506211 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-ahfs ahfs:24:24.00 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-atc atc:C07AB02 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-chebi chebi:6904 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-dpd dpd:2253518 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-kegg kegg:C07202 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-kegg kegg:D02358 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-pharmgkb pharmgkb:PA450480 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-wikipedia wikipedia:Metoprolol assertion.
• drugbank:DB00264 drugbank_vocabulary:x-bindingdb bindingdb:25756 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-ndc ndc:58177-293-04 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-gtp gtp:553 assertion.
• drugbank:DB00264 drugbank_vocabulary:x-iuphar iuphar:553 assertion.