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- drugbank:DB00270 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00270 label "Isradipine [drugbank:DB00270]" assertion.
- drugbank:DB00270 seeAlso DB00270 assertion.
- drugbank:DB00270 seeAlso isradipine.html assertion.
- drugbank:DB00270 seeAlso dyn1152.shtml assertion.
- drugbank:DB00270 seeAlso israd.htm assertion.
- drugbank:DB00270 identifier "drugbank:DB00270" assertion.
- drugbank:DB00270 description "Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and arterial smooth muscle cells. It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells. Isradipine may be used to treat mild to moderate essential hypertension." assertion.
- drugbank:DB00270 title "Isradipine" assertion.
- drugbank:DB00270 bio2rdf_vocabulary:identifier "DB00270" assertion.
- drugbank:DB00270 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00270 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00270" assertion.
- drugbank:DB00270 bio2rdf_vocabulary:x-identifiers.org DB00270 assertion.
- drugbank:DB00270 drugbank_vocabulary:drugbank-id "APRD00298" assertion.
- drugbank:DB00270 drugbank_vocabulary:drugbank-id "DB00270" assertion.
- drugbank:DB00270 drugbank_vocabulary:x-cas cas:75695-93-1 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-chemspider chemspider:3652 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-pubchemcompound pubchem.compound:3784 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46505034 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-ahfs ahfs:24:28.08 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-atc atc:C08CA03 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-kegg kegg:D00349 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-pharmgkb pharmgkb:PA450131 assertion.
- drugbank:DB00270 drugbank_vocabulary:x-wikipedia wikipedia:Isradipine assertion.
- drugbank:DB00270 drugbank_vocabulary:x-ndc ndc:0173-0784-01 assertion.