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- drugbank:DB00530 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00530 label "Erlotinib [drugbank:DB00530]" assertion.
- drugbank:DB00530 seeAlso DB00530 assertion.
- drugbank:DB00530 seeAlso erlotinib.html assertion.
- drugbank:DB00530 seeAlso tarceva.htm assertion.
- drugbank:DB00530 identifier "drugbank:DB00530" assertion.
- drugbank:DB00530 description "Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders." assertion.
- drugbank:DB00530 title "Erlotinib" assertion.
- drugbank:DB00530 bio2rdf_vocabulary:identifier "DB00530" assertion.
- drugbank:DB00530 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00530 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00530" assertion.
- drugbank:DB00530 bio2rdf_vocabulary:x-identifiers.org DB00530 assertion.
- drugbank:DB00530 drugbank_vocabulary:drugbank-id "APRD00951" assertion.
- drugbank:DB00530 drugbank_vocabulary:drugbank-id "DB00530" assertion.
- drugbank:DB00530 drugbank_vocabulary:x-cas cas:183321-74-6 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-chemspider chemspider:154044 assertion.
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- drugbank:DB00530 drugbank_vocabulary:x-pubchemcompound pubchem.compound:176870 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46508021 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-ahfs ahfs:10:00.00 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-atc atc:L01XE03 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-chebi chebi:114785 assertion.
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- drugbank:DB00530 drugbank_vocabulary:x-kegg kegg:D07907 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-pharmgkb pharmgkb:PA134687924 assertion.
- drugbank:DB00530 drugbank_vocabulary:x-wikipedia wikipedia:Erlotinib assertion.
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- drugbank:DB00530 drugbank_vocabulary:x-ndc ndc:54868-5447-0 assertion.