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- drugbank:DB00678 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00678 label "Losartan [drugbank:DB00678]" assertion.
- drugbank:DB00678 seeAlso DB00678 assertion.
- drugbank:DB00678 seeAlso losartan.html assertion.
- drugbank:DB00678 seeAlso losar.htm assertion.
- drugbank:DB00678 identifier "drugbank:DB00678" assertion.
- drugbank:DB00678 description "Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure." assertion.
- drugbank:DB00678 title "Losartan" assertion.
- drugbank:DB00678 bio2rdf_vocabulary:identifier "DB00678" assertion.
- drugbank:DB00678 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00678 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00678" assertion.
- drugbank:DB00678 bio2rdf_vocabulary:x-identifiers.org DB00678 assertion.
- drugbank:DB00678 drugbank_vocabulary:drugbank-id "APRD00052" assertion.
- drugbank:DB00678 drugbank_vocabulary:drugbank-id "DB00678" assertion.
- drugbank:DB00678 drugbank_vocabulary:x-cas cas:114798-26-4 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-chemspider chemspider:3824 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-pubchemcompound pubchem.compound:3961 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506538 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-ahfs ahfs:24:32.08 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-atc atc:C09CA01 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-chebi chebi:6541 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-dpd dpd:2182882 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-kegg kegg:C07072 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-kegg kegg:D08146 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-pharmgkb pharmgkb:PA450268 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-wikipedia wikipedia:Losartan assertion.
- drugbank:DB00678 drugbank_vocabulary:x-ndc ndc:0006-0951-54 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-gtp gtp:590 assertion.
- drugbank:DB00678 drugbank_vocabulary:x-iuphar iuphar:590 assertion.