Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01023_nanopub.RAQjRBfNfipGhh1hLOrHvqr2YOtfXJM8xZ8cRYl1cvyNw#assertion>. }
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- drugbank:DB01023 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01023 label "Felodipine [drugbank:DB01023]" assertion.
- drugbank:DB01023 seeAlso DB01023 assertion.
- drugbank:DB01023 seeAlso felodipine.html assertion.
- drugbank:DB01023 seeAlso rx-mono.aspx?contentFileName=ple1339.html&contentName=Plendil&contentId=593 assertion.
- drugbank:DB01023 seeAlso felo.htm assertion.
- drugbank:DB01023 identifier "drugbank:DB01023" assertion.
- drugbank:DB01023 description "Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins, exhibits competitive antagonism of the mineralcorticoid receptor, inhibits the activity of calmodulin-dependent cyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels. Felodipine is used to treat mild to moderate essential hypertension." assertion.
- drugbank:DB01023 title "Felodipine" assertion.
- drugbank:DB01023 bio2rdf_vocabulary:identifier "DB01023" assertion.
- drugbank:DB01023 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01023 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01023" assertion.
- drugbank:DB01023 bio2rdf_vocabulary:x-identifiers.org DB01023 assertion.
- drugbank:DB01023 drugbank_vocabulary:drugbank-id "APRD00374" assertion.
- drugbank:DB01023 drugbank_vocabulary:drugbank-id "DB01023" assertion.
- drugbank:DB01023 drugbank_vocabulary:x-cas cas:72509-76-3 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-chemspider chemspider:3216 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-pubchemcompound pubchem.compound:3333 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506968 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-ahfs ahfs:24:28.08 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-atc atc:C08CA02 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-chebi chebi:585948 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-dpd dpd:2222000 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-kegg kegg:D00319 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-pharmgkb pharmgkb:PA449591 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-wikipedia wikipedia:Felodipine assertion.
- drugbank:DB01023 drugbank_vocabulary:x-bindingdb bindingdb:50017710 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-ndc ndc:0378-5011-01 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-gtp gtp:4190 assertion.
- drugbank:DB01023 drugbank_vocabulary:x-iuphar iuphar:4190 assertion.