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- drugbank:DB01259 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01259 label "Lapatinib [drugbank:DB01259]" assertion.
- drugbank:DB01259 seeAlso DB01259 assertion.
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- drugbank:DB01259 seeAlso tykerb.htm assertion.
- drugbank:DB01259 identifier "drugbank:DB01259" assertion.
- drugbank:DB01259 description "Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug Capecitabine. Lapatinib is human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor. It binds to the intracellular phosphorylation domain to prevent receptor autophosphorylation upon ligand binding." assertion.
- drugbank:DB01259 title "Lapatinib" assertion.
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- drugbank:DB01259 drugbank_vocabulary:drugbank-id "DB02584" assertion.
- drugbank:DB01259 drugbank_vocabulary:x-cas cas:388082-78-8 assertion.
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- drugbank:DB01259 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507141 assertion.
- drugbank:DB01259 drugbank_vocabulary:x-atc atc:L01XE07 assertion.
- drugbank:DB01259 drugbank_vocabulary:x-chebi chebi:49603 assertion.
- drugbank:DB01259 drugbank_vocabulary:x-kegg kegg:D04024 assertion.
- drugbank:DB01259 drugbank_vocabulary:x-pharmgkb pharmgkb:PA152241907 assertion.
- drugbank:DB01259 drugbank_vocabulary:x-wikipedia wikipedia:Lapatinib assertion.
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- drugbank:DB01259 drugbank_vocabulary:x-ndc ndc:0173-0752-00 assertion.