Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01281_nanopub.RAgAOJL8oy-1U9r-XCeBSgR4sLhNfCResQB2atOf8d6AM#assertion>. }
Showing items 1 to 21 of
21
with 100 items per page.
- drugbank:DB01281 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01281 label "Abatacept [drugbank:DB01281]" assertion.
- drugbank:DB01281 seeAlso DB01281 assertion.
- drugbank:DB01281 seeAlso abatacept.html assertion.
- drugbank:DB01281 seeAlso orencia.htm assertion.
- drugbank:DB01281 identifier "drugbank:DB01281" assertion.
- drugbank:DB01281 description "Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. Although approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077)." assertion.
- drugbank:DB01281 title "Abatacept" assertion.
- drugbank:DB01281 bio2rdf_vocabulary:identifier "DB01281" assertion.
- drugbank:DB01281 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01281 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01281" assertion.
- drugbank:DB01281 bio2rdf_vocabulary:x-identifiers.org DB01281 assertion.
- drugbank:DB01281 drugbank_vocabulary:drugbank-id "DB01281" assertion.
- drugbank:DB01281 drugbank_vocabulary:x-cas cas:332348-12-6 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-ahfs ahfs:92:00.00 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-atc atc:L04AA24 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-dpd dpd:2282097 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-kegg kegg:D03203 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164747080 assertion.
- drugbank:DB01281 drugbank_vocabulary:x-wikipedia wikipedia:Abatacept assertion.
- drugbank:DB01281 drugbank_vocabulary:x-ndc ndc:0003-2187-10 assertion.