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- drugbank:DB01382 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01382 label "Glycodiazine [drugbank:DB01382]" assertion.
- drugbank:DB01382 seeAlso DB01382 assertion.
- drugbank:DB01382 identifier "drugbank:DB01382" assertion.
- drugbank:DB01382 description "Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. It is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus." assertion.
- drugbank:DB01382 title "Glycodiazine" assertion.
- drugbank:DB01382 bio2rdf_vocabulary:identifier "DB01382" assertion.
- drugbank:DB01382 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01382 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01382" assertion.
- drugbank:DB01382 bio2rdf_vocabulary:x-identifiers.org DB01382 assertion.
- drugbank:DB01382 drugbank_vocabulary:drugbank-id "DB01382" assertion.
- drugbank:DB01382 drugbank_vocabulary:x-cas cas:339-44-6 assertion.
- drugbank:DB01382 drugbank_vocabulary:x-chemspider chemspider:9190 assertion.
- drugbank:DB01382 drugbank_vocabulary:x-pubchemcompound pubchem.compound:9565 assertion.
- drugbank:DB01382 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507076 assertion.
- drugbank:DB01382 drugbank_vocabulary:x-atc atc:A10BC01 assertion.
- drugbank:DB01382 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164748839 assertion.