Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01583_nanopub.RAwQxKcIPhY6m6kH-bVzBxnhR9z06s6oA9k8NB6jbR4UQ#assertion>. }
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- drugbank:DB01583 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01583 label "Liotrix [drugbank:DB01583]" assertion.
- drugbank:DB01583 seeAlso DB01583 assertion.
- drugbank:DB01583 seeAlso liotrix.html assertion.
- drugbank:DB01583 seeAlso liot.htm assertion.
- drugbank:DB01583 identifier "drugbank:DB01583" assertion.
- drugbank:DB01583 description "Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion. It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. Administration of levothyroxine alone is sufficient for maintaining serum T4 and T3 levels in most patients and combination hormone replacement therapy generally offers no therapeutic advantage. In fact, administration of T3 may result in supratherapeutic levels of T3." assertion.
- drugbank:DB01583 title "Liotrix" assertion.
- drugbank:DB01583 bio2rdf_vocabulary:identifier "DB01583" assertion.
- drugbank:DB01583 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01583 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01583" assertion.
- drugbank:DB01583 bio2rdf_vocabulary:x-identifiers.org DB01583 assertion.
- drugbank:DB01583 drugbank_vocabulary:drugbank-id "DB01583" assertion.
- drugbank:DB01583 drugbank_vocabulary:x-cas cas:8065-29-0 assertion.
- drugbank:DB01583 drugbank_vocabulary:x-chemspider chemspider:64467 assertion.
- drugbank:DB01583 drugbank_vocabulary:x-pubchemcompound pubchem.compound:71371 assertion.
- drugbank:DB01583 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506203 assertion.
- drugbank:DB01583 drugbank_vocabulary:x-ahfs ahfs:68:36.04 assertion.
- drugbank:DB01583 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164748036 assertion.