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- drugbank:DB04571 type drugbank_vocabulary:Drug assertion.
- drugbank:DB04571 label "Trioxsalen [drugbank:DB04571]" assertion.
- drugbank:DB04571 seeAlso DB04571 assertion.
- drugbank:DB04571 seeAlso trioxsalen.html assertion.
- drugbank:DB04571 identifier "drugbank:DB04571" assertion.
- drugbank:DB04571 description "Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative. It is obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo[1] and hand eczema.[2] After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms. In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage.[3] The compound is also being explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair." assertion.
- drugbank:DB04571 title "Trioxsalen" assertion.
- drugbank:DB04571 bio2rdf_vocabulary:identifier "DB04571" assertion.
- drugbank:DB04571 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB04571 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB04571" assertion.
- drugbank:DB04571 bio2rdf_vocabulary:x-identifiers.org DB04571 assertion.
- drugbank:DB04571 drugbank_vocabulary:drugbank-id "DB04571" assertion.
- drugbank:DB04571 drugbank_vocabulary:x-cas cas:3902-71-4 assertion.
- drugbank:DB04571 drugbank_vocabulary:x-atc atc:D05AD01 assertion.
- drugbank:DB04571 drugbank_vocabulary:x-kegg kegg:C09314 assertion.
- drugbank:DB04571 drugbank_vocabulary:x-kegg kegg:D01034 assertion.
- drugbank:DB04571 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164747186 assertion.
- drugbank:DB04571 drugbank_vocabulary:x-wikipedia wikipedia:Trioxsalen assertion.