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- drugbank:DB06681 type drugbank_vocabulary:Drug assertion.
- drugbank:DB06681 label "Belatacept [drugbank:DB06681]" assertion.
- drugbank:DB06681 seeAlso DB06681 assertion.
- drugbank:DB06681 seeAlso belatacept.html assertion.
- drugbank:DB06681 seeAlso nulojix-drug.htm assertion.
- drugbank:DB06681 identifier "drugbank:DB06681" assertion.
- drugbank:DB06681 description "Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. It is approved for the treatment of rheumatoid arthritis. Belatacept selectively blocks the process of T-cell activation. It was developed by Bristol-Myers-Squibb. It differs from abatacept (Orencia) by only 2 amino acids. FDA approved on June 15, 2011." assertion.
- drugbank:DB06681 title "Belatacept" assertion.
- drugbank:DB06681 bio2rdf_vocabulary:identifier "DB06681" assertion.
- drugbank:DB06681 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB06681 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB06681" assertion.
- drugbank:DB06681 bio2rdf_vocabulary:x-identifiers.org DB06681 assertion.
- drugbank:DB06681 drugbank_vocabulary:drugbank-id "DB06681" assertion.
- drugbank:DB06681 drugbank_vocabulary:x-cas cas:706808-37-9 assertion.
- drugbank:DB06681 drugbank_vocabulary:x-ahfs ahfs:92:44 assertion.
- drugbank:DB06681 drugbank_vocabulary:x-atc atc:L04AA28 assertion.
- drugbank:DB06681 drugbank_vocabulary:x-kegg kegg:D03222 assertion.
- drugbank:DB06681 drugbank_vocabulary:x-wikipedia wikipedia:Belatacept assertion.
- drugbank:DB06681 drugbank_vocabulary:x-ndc ndc:0003-0371-13 assertion.