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- drugbank:DB08895 type drugbank_vocabulary:Drug assertion.
- drugbank:DB08895 label "Tofacitinib [drugbank:DB08895]" assertion.
- drugbank:DB08895 seeAlso DB08895 assertion.
- drugbank:DB08895 seeAlso xeljanz.html assertion.
- drugbank:DB08895 seeAlso tofacitinib assertion.
- drugbank:DB08895 seeAlso xeljanz-drug.htm assertion.
- drugbank:DB08895 identifier "drugbank:DB08895" assertion.
- drugbank:DB08895 description "Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signaling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. Besides rheumatoid arthritis, tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and the treatment of psoriasis and ulcerative colitis. Known adverse effects include nausea and headache as well as more serious immunologic and hematological adverse effects. Tofacitinib is marketed under the brand name Xeljanz." assertion.
- drugbank:DB08895 title "Tofacitinib" assertion.
- drugbank:DB08895 bio2rdf_vocabulary:identifier "DB08895" assertion.
- drugbank:DB08895 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB08895 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB08895" assertion.
- drugbank:DB08895 bio2rdf_vocabulary:x-identifiers.org DB08895 assertion.
- drugbank:DB08895 drugbank_vocabulary:drugbank-id "DB08895" assertion.
- drugbank:DB08895 drugbank_vocabulary:x-cas cas:477600-75-2 assertion.
- drugbank:DB08895 drugbank_vocabulary:x-ahfs ahfs:92:36 assertion.
- drugbank:DB08895 drugbank_vocabulary:x-atc atc:L04AA29 assertion.
- drugbank:DB08895 drugbank_vocabulary:x-chebi chebi:71200 assertion.
- drugbank:DB08895 drugbank_vocabulary:x-kegg kegg:D09970 assertion.
- drugbank:DB08895 drugbank_vocabulary:x-wikipedia wikipedia:Tofacitinib assertion.
- drugbank:DB08895 drugbank_vocabulary:x-ndc ndc:63539-012-02 assertion.