Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank_resource:DB00203_DB00872_nanopub.RAOp_x3rtCMBNgEaUesKgW3AqrTRwagCaBYFcHKzsfc90#assertion>. }
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- drugbank_resource:DB00203_DB00872 type drugbank_vocabulary:Drug-Drug-Interaction assertion.
- drugbank_resource:DB00203_DB00872 label "DDI between Sildenafil and Conivaptan - CYP3A4 Inhibitors (Strong) such as conivaptan may increase the serum concentration of Sildenafil. When sildenanfil is used for treatment of pulmonary arterial hypertension, concurrent use with strong CYP3A4 inhibitors is not recommended. When sildenafil is used for treatment of erectile dysfunction, consider using a lower starting dose of 25 mg in patients who are also taking a strong CYP3A4 inhibitor. Due to the particularly strong effects of ritonavir, sildenafil (for erectile dysfunction) doses greater than 25 mg per 48 hours are not recommended. Of note, the interaction between CYP3A4 inhibitors and sildenafil is predicted to be greater with orally administered than with injected sildenafil. [drugbank_resource:DB00203_DB00872]" assertion.
- drugbank_resource:DB00203_DB00872 identifier "drugbank_resource:DB00203_DB00872" assertion.
- drugbank_resource:DB00203_DB00872 title "DDI between Sildenafil and Conivaptan - CYP3A4 Inhibitors (Strong) such as conivaptan may increase the serum concentration of Sildenafil. When sildenanfil is used for treatment of pulmonary arterial hypertension, concurrent use with strong CYP3A4 inhibitors is not recommended. When sildenafil is used for treatment of erectile dysfunction, consider using a lower starting dose of 25 mg in patients who are also taking a strong CYP3A4 inhibitor. Due to the particularly strong effects of ritonavir, sildenafil (for erectile dysfunction) doses greater than 25 mg per 48 hours are not recommended. Of note, the interaction between CYP3A4 inhibitors and sildenafil is predicted to be greater with orally administered than with injected sildenafil." assertion.
- drugbank:DB00872 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00203_DB00872 assertion.
- drugbank:DB00203 drugbank_vocabulary:ddi-interactor-in drugbank_resource:DB00203_DB00872 assertion.