Matches in Nanopublications for { ?s ?p ?o <http://purl.org/np/RAoAA5b8Ye07n8lagOneMsxSG-m63sBR1lOaduJS-oMWY#assertion>. }
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- context type Cohort assertion.
- association type Statement assertion.
- DRUGBANK:DB00656 type Drug assertion.
- MONDO_0013600 type Disease assertion.
- context label "elderly" assertion.
- association label "Trazodone, the most sedating atypical antidepressant, is widely used as an off-label hypnotic especially in the elderly. Although generally considered safe, it can potentially inhibit midbrain dopaminergic neurotransmission leading to the emergence of extrapyramidal adverse effects. Two previous cases of trazodone-induced parkinsonism have been described after its prolonged use as an antidepressant; however, there is no published case of secondary parkinsonism caused by trazodone in a nondepressed person after its use as a hypnotic. Here, we present a case of rapid development of bradykinetic-rigid parkinsonism temporally linked to the use of trazodone as a hypnotic in a nondepressed elderly man" assertion.
- association object MONDO_0013600 assertion.
- association predicate treats assertion.
- association subject DRUGBANK:DB00656 assertion.
- association relation OffLabelIndication assertion.
- association publications 29634584 assertion.
- association provided_by NeuroDKG assertion.
- association has_population_context context assertion.