Matches in Nanopublications for { ?s ?p ?o <http://rdf.disgenet.org/nanopublications.trig#NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance>. }
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- source_evidence_curated type ECO_0000205 NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- source_evidence_curated label "DisGeNET evidence - CURATED" NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- source_evidence_curated comment "Gene-disease associations manually curated." NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion description "[Results of the present study indicate that 1) PGE(2) promotes survival of human endometriotic cells through EP2 and EP4 receptors by activating ERK1/2, AKT, nuclear factor-kappaB, and beta-catenin signaling pathways; 2) selective inhibition of EP2 and EP4 suppresses these cell survival pathways and augments interactions between proapoptotic proteins (Bax and Bad) and antiapoptotic proteins (Bcl-2/Bcl-XL), facilitates the release of cytochrome c, and thus activates caspase-3/poly (ADP-ribose) polymerase-mediated intrinsic apoptotic pathways; and 3) these PGE(2) signaling components are more abundantly expressed in ectopic endometriosis tissues compared with eutopic endometrial tissues during the menstrual cycle in women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion evidence source_evidence_curated NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion SIO_000772 19407222 NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion wasDerivedFrom ctd_human-20130708 NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_assertion wasGeneratedBy ECO_0000218 NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.
- ctd_human-20130708 importedOn "2013-07-24" NP27611.RAXHb5Onwdc-rEPcTHSPXr9TnONe-EfxynMNV3fljXbp0130_provenance.