Matches in Nanopublications for { ?s ?p ?o <http://rdf.disgenet.org/nanopublications.trig#NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance>. }
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- source_evidence_literature type ECO_0000212 NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_assertion description "[Psychotropic drugs can meaningfully affect PD risk gene mRNA transcription, including antipsychotics (upregulate dopamine receptors D2 and D3 (DRD2, DRD3); downregulate low-density lipoprotein receptor-related protein 8 (LRP8), ubiquitin carboxyl-terminal esterase L1 (UCHL1, also known as PARK5)), haloperidol (upregulates DRD3, parkin (PRKN, also known as PARK2), DRD2; downregulates brain-derived neurotrophic factor (BDNF)), risperidone (upregulates monoamine oxidase B (MAOB), DRD2), olanzapine (upregulates transmembrane protein 163 (TMEM163), BDNF, glutathione S-transferase mu 1 (GSTM1), MAOB, DRD2, solute carrier organic anion transporter family, member 3A1 (SLCO3A1)), aripiprazole (upregulates DRD2), quetiapine, paliperidone, lurasidone, carbamazepine, and many antidepressants (upregulate BDNF), lithium and bupropion (downregulate BDNF), amitriptyline (upregulates DRD3, DRD2), imipramine (upregulates BDNF, DRD3, DRD2), desipramine (upregulates BDNF, DRD3), and fluoxetine (upregulates acid beta-glucosidase (GBA), coiled-coil domain containing 62 (CCDC62), BDNF, DRD3, UCHL1, unc-13 homolog B (UNC13B), and perhaps huntingtin interacting protein 1 related (HIP1R); downregulates microtubule-associated protein tau (MAPT), methylcrotonoyl-coenzyme A carboxylase I (MCCC1), GSTM1, 28kDa calbindin 1 (CALB1)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_assertion evidence source_evidence_literature NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_assertion SIO_000772 22507762 NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_assertion wasDerivedFrom befree-20140225 NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_assertion wasGeneratedBy ECO_0000203 NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.
- befree-20140225 importedOn "2014-02-25" NP478755.RAZG3liXJJyWa1CdrY-5_AC9NQnkRF2nELcj59DtI0IF0130_provenance.