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- source_evidence_literature type ECO_0000212 NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_assertion description "[RA, co-administered with the dsRNA mimicker polyinosinic-polycytidylic acid (poly(I:C)), synergizes to mount a specific response program able to sense dsRNA through the concurrent upregulation of TLR3, the dsRNA helicases melanoma differentiation-associated antigen-5 (MDA-5) and RA-inducible gene-1 (RIG-1), and the dsRNA-activated protein kinase (PKR) expression, leading breast cancer cells to specifically express downstream transcriptional targets of dsRNA sensors, such as interferon-? (IFN?), interleukin-8 (IL-8), chemokine (C-C motif) ligand 5 (CCL5), and C-X-C motif Chemokine 10 (CXCL10).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_assertion evidence source_evidence_literature NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_assertion SIO_000772 23370279 NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_assertion wasDerivedFrom befree-20140225 NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_assertion wasGeneratedBy ECO_0000203 NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.
- befree-20140225 importedOn "2014-02-25" NP718687.RATzuSYMpV_pcQT60fRRj-WhTTkm_4Nqj80u9ltplbAVQ130_provenance.