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- source_evidence_literature type ECO_0000212 NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_assertion description "[Using pancreatic cancer microarrays and immunohistochemistry, we determined that 6% (4 of 46 and 5 of 100 in two independent panels) of pancreatic adenocarcinomas overexpress cyclin E. We identified two potential mechanisms for this overexpression including the amplification/gain of CCNE1 gene copies in the Panc-1 and Su86.86 cell lines and a novel somatic homozygous mutation (H460R, in one of 11 pancreatic cancer xenografts having allelic loss) in FBXW7, which was accompanied by cyclin E overexpression by immunohistochemistry.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_assertion evidence source_evidence_literature NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_assertion SIO_000772 14507635 NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_assertion wasDerivedFrom befree-20140225 NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_assertion wasGeneratedBy ECO_0000203 NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.
- befree-20140225 importedOn "2014-02-25" NP928410.RAgjfG_w1tec_nrlhI-OJ8-HufbTMA34hOkZU4eExTRwY130_provenance.