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- source_evidence_literature type ECO_0000212 NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_assertion description "[This interaction is functional; overexpression of FTO delays the dephosphorylation of cAMP response element-binding protein (CREB) in human neuroblastoma (SK-N-SH) cells, which in turn leads to a dramatic increase in the expression of the CREB targets neuropeptide receptor 1 (NPY1R) and brain-derived neurotrophic factor (BDNF), which already are known to regulate food intake and energy homeostasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_assertion evidence source_evidence_literature NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_assertion SIO_000772 24488767 NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_assertion wasDerivedFrom befree-2016 NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_assertion wasGeneratedBy ECO_0000203 NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.
- befree-2016 importedOn "2016-02-19" NP1151389.RAoNDzaIDKVFmzsuHiage1wLxlnA0hZMBK5Itr9qj8-zc130_provenance.