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- source_evidence_literature type ECO_0000212 NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_assertion description "[These findings suggest that (1) LB pathology can influence the clinical features of familial AD, (2) the E184D mutation of presenilin-1 may be associated with the LB formation through Abeta overproduction, although the process of LB formation is strongly affected by other unknown mechanisms, (3) in neurodegenerative disorders with LBs, there is a common pathophysiological background inducing NAC accumulation in neuritic plaques and astrocytes, and (4) the NAC accumulation in neuritic plaques is modulated by the abnormally aggregated tau protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_assertion evidence source_evidence_literature NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_assertion SIO_000772 12410385 NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_assertion wasDerivedFrom befree-2016 NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_assertion wasGeneratedBy ECO_0000203 NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.
- befree-2016 importedOn "2016-02-19" NP373128.RAhbgwa75uiXhtwkA1IWgecYT4KrBESCOXfAAlWxd9YsY130_provenance.