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- source_evidence_literature type ECO_0000212 NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_assertion description "[In this study, we demonstrate for the first time that 17?-estradiol (E2) and the selective GPER ligand G-1 regulate FASN expression and activity through the GPER-mediated signaling, which involved the EGF receptor/ERK/c-Fos/AP1 transduction pathway, as ascertained by using specific pharmacological inhibitors, performing gene-silencing experiments and ChIP assays in breast SkBr3, colorectal LoVo, hepatocarcinoma HepG2 cancer cells, and breast cancer-associated fibroblasts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_assertion evidence source_evidence_literature NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_assertion SIO_000772 23135268 NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_assertion wasDerivedFrom befree-20150227 NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_assertion wasGeneratedBy ECO_0000203 NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.
- befree-20150227 importedOn "2015-02-27" NP394923.RAb8f1cbgKCOSsIb0x7f3mS0UwIaP7pi0G36UIt5BeLKI130_provenance.