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- source_evidence_literature type ECO_0000212 NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_assertion description "[In this study, we demonstrate for the first time that 17?-estradiol (E2) and the selective GPER ligand G-1 regulate FASN expression and activity through the GPER-mediated signaling, which involved the EGF receptor/ERK/c-Fos/AP1 transduction pathway, as ascertained by using specific pharmacological inhibitors, performing gene-silencing experiments and ChIP assays in breast SkBr3, colorectal LoVo, hepatocarcinoma HepG2 cancer cells, and breast cancer-associated fibroblasts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_assertion evidence source_evidence_literature NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_assertion SIO_000772 23135268 NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_assertion wasDerivedFrom befree-20150227 NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_assertion wasGeneratedBy ECO_0000203 NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.
- befree-20150227 importedOn "2015-02-27" NP395421.RAS19qwvZ0nLEdQlSWCj9YO3wZ07SnHpJCgd-ACKtoyXk130_provenance.