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- source_evidence_literature type ECO_0000212 NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_assertion description "[We found that long-term exposure to hypoxia a) significantly inhibited lung cancer tumor growth in xenograft and orthotopic models in rats, b) significantly reduced lymphatic metastasis of the lung cancer in rats and decreased lung metastasis of Lewis lung carcinoma in mice, c) reduced lung cancer cell proliferation and cell cycle progression in vitro, d) decreased growth of the tumors from hypoxia-pretreated A549 cells, e) decreased Na+-K+ ATPase ?1 expression in hypoxic lung cancer tumors, and f) increased expression of hypoxia inducible factors (HIF1? and HIF2?) but decreased microvessel density in the lung cancer tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_assertion evidence source_evidence_literature NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_assertion SIO_000772 21812995 NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_assertion wasDerivedFrom befree-20150227 NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_assertion wasGeneratedBy ECO_0000203 NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.
- befree-20150227 importedOn "2015-02-27" NP449396.RArizUtEoO9eLB10U3ttZZ53htWUY-s090656sjAn8hug130_provenance.